Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517648 | 0.86 | HSD17B1 (0.46) | HSD17B1HSD17B2CYP3A4CYP2C9SREBF2 | |
| Phenol SCHEMBL11781187 | 0.86 | PPARA (0.48) | PTGER1PTGER4PTGER3PTGER2PPARA | |
| SCHEMBL18687702 | 0.84 | HSD17B1 (0.52) | PTGER1PTGER4PTGER3PTGER2HSD17B1 | |
| SCHEMBL7710601 | 0.83 | ADRA2C (0.60) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL5274698 | 0.82 | HSD17B1 (0.47) | HSD17B1HSD17B2CYP3A4CYP2C9SREBF2 | |
| SCHEMBL6048555 | 0.82 | SRC (0.52) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL7710788 | 0.81 | ADRA2C (0.59) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL6048546 | 0.81 | SRC (0.51) | ABCB1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL15238829 | 0.81 | HTR7 (0.50) | PTGER1PTGER4PTGER3PTGER2ADRA2C | |
| SCHEMBL26545737 | 0.81 | FFAR1 (0.47) | PTGER1PTGER4PTGER3PTGER2ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598480-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | Oryzon Genomics, S.A. (ES) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013727-A1 | CYCLOPROPYLAMINE DERIVATIVES USEFUL AS LSD1 INHIBITORS | ORYZON GENOMICS S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |