Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 15/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5277443 | 0.90 | SMN1; SMN2 (0.34) | CD274PDCD1ALDH1A1HPGD | |
| SCHEMBL5276249 | 0.87 | SMYD2 (0.33) | CD274PDCD1ALDH1A1HPGD | |
| SCHEMBL5273043 | 0.87 | ALDH1A1 (0.37) | ALDH1A1HPGD | |
| SCHEMBL5804676 | 0.87 | ALDH1A1 (0.35) | CD274PDCD1ALDH1A1 | |
| SCHEMBL6027383 | 0.87 | OPRM1 (0.36) | CD274PDCD1ALDH1A1HDAC1 | |
| SCHEMBL6027738 | 0.84 | ESRRG (0.40) | CD274PDCD1HDAC1 | |
| SCHEMBL4692560 | 0.84 | CD274 (0.39) | CD274PDCD1HDAC1 | |
| SCHEMBL4696335 | 0.84 | PDCD1 (0.44) | CD274PDCD1ALDH1A1 | |
| SCHEMBL4691952 | 0.81 | PDCD1 (0.35) | CD274PDCD1ALDH1A1 | |
| SCHEMBL4695511 | 0.81 | PDCD1 (0.34) | CD274PDCD1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856048-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006098999-A1 | BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2006-09-21 | — | — | WO | disclosed |