Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2574086 | 0.75 | OPRK1 (0.33) | — | |
| SCHEMBL18580634 | 0.72 | PARP1 (0.36) | — | |
| SCHEMBL308762 | 0.72 | PARP1 (0.36) | — | |
| SCHEMBL17821466 | 0.71 | SIGMAR1 (0.36) | — | |
| SCHEMBL28305317 | 0.71 | THRA (0.37) | THRATHRB | |
| SCHEMBL22341315 | 0.70 | — | — | |
| SCHEMBL10903692 | 0.70 | SMN1; SMN2 (0.39) | POLB | |
| SCHEMBL10903685 | 0.70 | SMN1; SMN2 (0.39) | POLB | |
| SCHEMBL24449449 | 0.69 | NR1H2 (0.43) | — | |
| SCHEMBL2081015 | 0.69 | RIPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014109-A1 | HETEROCYCLIC SULFONAMIDES AS INHIBITORS OF TRANSFER RNA SYNTHETASE FOR USE AS ANTIBACTERIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |