SCHEMBL5278922

SCHEMBL5278922

NC(CC(=O)O)CC(N)(CC(=O)O)CC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.37
GABRR1 P24046 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
LMNA P02545 1/20 0.33
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HMGCR P04035 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
ANPEP P15144 2/20 0.30
ENPEP Q07075 2/20 0.30
S1PR2 O95136 1/20 0.30
S1PR1 P21453 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5379381 0.91 LMNA (0.34) TDP1GABRR1LMNAKDM4ESMN1; SMN2
SCHEMBL10587729 0.80 TDP1 (0.39) TDP1GABRR1SLC22A6LMNAKDM4E
SCHEMBL5691964 0.79 TDP1 (0.34) TDP1GABRR1SLC22A6LMNAALDH1A1
SCHEMBL27739561 0.73 SLC22A6 (0.36) TDP1GABRR1SLC22A6LMNASMN1; SMN2
SCHEMBL1964906 0.73 SLC22A6 (0.36) TDP1GABRR1SLC22A6LMNAKDM4E
SCHEMBL6463849 0.73 SLC22A6 (0.36) TDP1GABRR1SLC22A6LMNAKDM4E
SCHEMBL288405 0.73 SLC22A6 (0.36) TDP1GABRR1SLC22A6LMNAKDM4E
SCHEMBL288510 0.72 SLC22A6 (0.50) TDP1GABRR1SLC22A6LMNASMN1; SMN2
SCHEMBL16374685 0.72 ALDH1A1 (0.45) TDP1LMNAKDM4EALDH1A1HMGCR
SCHEMBL8008505 0.71 ALDH1A1 (0.33) ALDH1A1CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240076541-A1 RESIN COMPOSITION AND LIGHT-EMITTING DEVICE NICHIA CORPORATION (JP) 2024-03-07 US claimed
EP-1465251-B1 Method for producing metal/ceramic bonded substrate DOWA METALTECH CO LTD (JP) 2019-01-23 EP claimed
US-7219826-B2 Forming a desired fillet on the peripheral portion of a metal circuit; brazing DOWA MINING CO., LTD. (JP) 2007-05-22 US claimed
US-20040262367-A1 Forming a desired fillet on the peripheral portion of a metal circuit; brazing DOWA METALTECH CO., LTD. (JP) 2004-12-30 US claimed
EP-1465251-A2 Method for producing metal/ceramic bonded substrate Dowa Mining Co., Ltd. (JP) 2004-10-06 EP claimed
US-20240076541-A1 RESIN COMPOSITION AND LIGHT-EMITTING DEVICE NICHIA CORPORATION (JP) 2024-03-07 US disclosed
WO-2023013718-A1 LIQUID DETERGENT COMPOSITION FOR DISHWASHING MACHINES 花王株式会社 2023-02-09 WO disclosed
EP-2916627-B1 METHOD FOR MANUFACTURING CERAMIC CIRCUIT BOARD HITACHI METALS LTD (JP) 2019-04-03 EP disclosed
EP-1465251-B1 Method for producing metal/ceramic bonded substrate DOWA METALTECH CO LTD (JP) 2019-01-23 EP disclosed
US-10104783-B2 Method for producing ceramic circuit board HITACHI METALS, LTD. (JP) 2018-10-16 US disclosed
US-20160192503-A1 METHOD FOR PRODUCING CERAMIC CIRCUIT BOARD HITACHI METALS, LTD. (JP) 2016-06-30 US disclosed
EP-2916627-A1 METHOD FOR MANUFACTURING CERAMIC CIRCUIT BOARD Hitachi Metals, Ltd. (JP) 2015-09-09 EP disclosed
EP-1465251-A2 Method for producing metal/ceramic bonded substrate Dowa Mining Co., Ltd. (JP) 2004-10-06 EP disclosed