SCHEMBL8008505

SCHEMBL8008505

NC(CC(N)(CC(=O)O)CC(=O)O)C(CC(=O)O)(CC(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
CPT2 P23786 1/20 0.31
ACLY P53396 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5278922 0.71 TDP1 (0.37) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL16374685 0.69 ALDH1A1 (0.45) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL5691964 0.68 TDP1 (0.34) ALDH1A1CPT2ACLY
SCHEMBL19258711 0.68 ALDH1A1 (0.46) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
Hydrochloric Acid SCHEMBL27533813 0.67 KDM4E (0.48) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL5691059 0.65 ALDH1A1 (0.41) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL125594 0.65 ALDH1A1 (0.41) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL5379381 0.64 LMNA (0.34) ALDH1A1CYP2D6TSHR
SCHEMBL23772237 0.64 CYP2C19 (0.46) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL12524010 0.64 ACLY (0.43) ALDH1A1CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6015653-A TREATING WITH PROCESSING SOLUTION CONTAINING SPECIFIED NITROGEN-CONTAINING HETEROCYCLIC SULFUR COMPOUND; DISCOLORATION INHIBITION KONICA CORPORATION (JP) 2000-01-18 US disclosed