Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280465 | 0.89 | EPHX2 (0.36) | ALDH1A1P2RX7POLBCHRM2CHRM1 | |
| SCHEMBL5279342 | 0.89 | EPHX2 (0.36) | ALDH1A1P2RX7POLBCHRM2CHRM1 | |
| SCHEMBL5280454 | 0.89 | EPHX2 (0.36) | ALDH1A1P2RX7POLBCHRM2CHRM1 | |
| SCHEMBL12917291 | 0.89 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL5279826 | 0.87 | P2RX7 (0.37) | ALDH1A1P2RX7POLBCHRM2CHRM1 | |
| SCHEMBL5164103 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1P2RX7POLBCHRM2 | |
| SCHEMBL5278268 | 0.83 | EPHX2 (0.36) | KDM4EALDH1A1P2RX7HPGDHSD17B10 | |
| SCHEMBL5282151 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL5274263 | 0.81 | ALDH1A1 (0.40) | ALDH1A1P2RX7POLBCHRM2CHRM1 | |
| SCHEMBL5284756 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1P2RX7HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768973-B1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO KG (DE) | 2007-12-05 | — | — | EP | disclosed |