Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20831303 | 0.82 | SLC9A1 (0.34) | GABRB3SLC9A1GRIA1GRIA2GRIA3 | |
| SCHEMBL5276162 | 0.82 | GABRB3 (0.40) | GABRB3SLC9A1GRIA1GRIA2GRIA3 | |
| Hydrochloric Acid SCHEMBL20818442 | 0.80 | SLC9A1 (0.33) | GABRB3SLC9A1GRIA1GRIA2GRIA3 | |
| SCHEMBL5279076 | 0.79 | MAOB (0.33) | GABRB3SLC9A1GRIA1GRIA2GRIA3 | |
| SCHEMBL5282072 | 0.79 | GRIA1 (0.39) | SLC9A1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5275895 | 0.76 | GABRB3 (0.37) | GABRB3SLC9A1GRIA1GRIA2GRIA3 | |
| SCHEMBL5277723 | 0.76 | SLC9A1 (0.46) | SLC9A1ALDH1A1GRM2TOP2A | |
| SCHEMBL765330 | 0.75 | — | — | |
| SCHEMBL5278971 | 0.74 | SLC9A1 (0.35) | SLC9A1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5276061 | 0.74 | GRM2 (0.39) | SLC9A1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014113485-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2014-07-24 | — | — | WO | disclosed |
| US-20140193337-A1 | 18F-SACCHARIDE-FOLATES | Merck & Cie (CH) | 2014-07-10 | — | — | US | disclosed |
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140193337-A1 | 18F-SACCHARIDE-FOLATES | FOLR1, FOLR2, FOLH1 | GABRB3 1669/4885SLC9A1 3439/4885GRIA1 275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.