Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279059 | 0.83 | GABRB3 (0.38) | GABRB3GABRA2GABRB2MAOA | |
| SCHEMBL5280268 | 0.81 | CACNA2D1 (0.33) | MAOACYP1A2CYP2C19POLBALDH1A1 | |
| SCHEMBL5273774 | 0.80 | MAOA (0.35) | GABRB3GABRA2GABRB2MAOA | |
| SCHEMBL5281595 | 0.78 | GABRB3 (0.35) | GABRB3GABRA2GABRB2CYP1A2CYP2C19 | |
| SCHEMBL5277345 | 0.78 | CYP1A2 (0.34) | GABRB3GABRA2GABRB2CYP1A2CYP2C19 | |
| SCHEMBL5279977 | 0.78 | MAOA (0.30) | MAOA | |
| SCHEMBL5279026 | 0.77 | TOP2A (0.32) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL5278341 | 0.77 | ALDH1A1 (0.30) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL5281328 | 0.77 | TOP2A (0.32) | CYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL5278231 | 0.75 | GABRB3 (0.40) | GABRB3GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10750742-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-25 | — | — | US | disclosed |
| US-20190014783-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-17 | — | — | US | disclosed |
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190014783-A1 | PESTICIDALLY ACTIVE PYRAZOLE DERIVATIVES | ACHE, AADAC, CAT | GABRB3 1064/4885GABRA2 2573/4885GABRB2 1705/4885 |
| US-10750742-B2 | Pesticidally active pyrazole derivatives | ACHE, AADAC, CAT | GABRB3 1064/4885GABRA2 2573/4885GABRB2 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.