Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041529 | 0.80 | POLQ (0.50) | ESR1POLQPOLBMAPK1KMT2A | |
| SCHEMBL13041505 | 0.73 | POLQ (0.47) | ESR1POLQPOLBMAPK1KMT2A | |
| SCHEMBL3399062 | 0.71 | POLQ (0.48) | ESR1POLQPOLBMAPK1KMT2A | |
| SCHEMBL11309832 | 0.70 | POLQ (0.50) | ESR1POLQACHEHDAC6LMNA | |
| SCHEMBL3266697 | 0.69 | POLQ (0.46) | ESR1POLQALDH1A1ACHEHDAC6 | |
| SCHEMBL1652095 | 0.68 | GAA (0.52) | ESR1POLQPOLBMAPK1KMT2A | |
| SCHEMBL9821084 | 0.68 | ALDH1A1 (0.44) | ESR1POLQPOLBKMT2AKDM4E | |
| SCHEMBL25076165 | 0.67 | TSPO (0.47) | ESR1POLQHDAC6LMNAGAA | |
| SCHEMBL5839377 | 0.67 | ESR1 (0.43) | ESR1POLQMAPK1HDAC6NOS3 | |
| Hydrochloric Acid SCHEMBL5718674 | 0.67 | ESR1 (0.43) | ESR1POLQPOLBMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853352-A2 | USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF | L'Oréal (FR) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006079568-A2 | USE OF 3-SULFANYLPROPANAMIDE DERIVATIVES FOR STIMULATING HAIR AND EYELASH GROWTH AND/OR FOR STOPPING THE LOSS AND/OR LIMITING THE DEPIGMENTATION THEREOF | L'OREAL (FR) | 2006-08-03 | — | — | WO | disclosed |