Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL122080 | 1.00 | TSHR (0.90) | — | |
| Maleic Acid SCHEMBL52799 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL453820 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL28080180 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL4816794 | 1.00 | TSHR (0.90) | — | |
| Maleic Acid SCHEMBL4816790 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL6468133 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL106605 | 1.00 | — | — | |
| Maleic Acid SCHEMBL7102604 | 0.95 | TSHR (0.82) | — | |
| Maleic Acid SCHEMBL3410757 | 0.95 | TSHR (0.82) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 10178 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144755-A1 | Solid Oral Dosage Forms Comprising Tavapadon | CEREVEL THERAPEUTICS, LLC (US) | 2026-05-28 | — | — | US | claimed |
| CN-122060429-A | Sodium-containing modified polyvinylidene fluoride binder and preparation method and application thereof | 江西量子新能源科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122037024-A | Preparation method of oil-soluble monodisperse black polymeric microspheres | 深圳市金准生物医学工程有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122035819-A | Sodium-rich hard carbon material, preparation method thereof and sodium ion battery | 广东海四达钠星技术有限公司 | 2026-05-15 | — | — | CN | claimed |
| US-20260132548-A1 | LYOCELL FIBER MODIFIED BY COMPOUND FLAME RETARDANT AND PREPARATIONS METHOD THEREOF | CHINA TEXTILE ACADEMY (CN) | 2026-05-14 | — | — | US | claimed |
| US-20260097044-A1 | ION PAIR LIQUID CRYSTAL FORMULATIONS FOR LONG-ACTING INJECTABLES OF POORLY SOLUBLE DRUGS | FORDOZ PHARMA CORP. (US) | 2026-04-09 | — | — | US | claimed |
| EP-4709359-A1 | ORAL DOSAGE FORMS OF METFORMIN AND PREPARATION METHOD THEREOF | Elite Pharmaceutical Solution Inc. (US) | 2026-03-18 | — | — | EP | claimed |
| EP-4707350-A1 | TREATMENT LIQUID COMPOSITION FOR DYE PRINTING, INK SET, AND RECORDING METHOD | Seiko Epson Corporation (JP) | 2026-03-11 | — | — | EP | claimed |
| CN-121586575-A | Metformin oral dosage form and method for preparing the same | 赛乐医药科技有限公司 | 2026-02-27 | — | — | CN | claimed |
| EP-4682143-A1 | PHARMACEUTICAL COMPOSITION CONTAINING EGFR INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Convalife Pharmaceuticals Co., Ltd. (CN) | 2026-01-21 | — | — | EP | claimed |
| EP-0048988-A1 | Method for forming decorative colored streak patterns on the surface of an aluminum shaped article | YOSHIDA KOGYO K.K. (JP) | 1982-04-07 | — | — | EP | claimed |
| EP-0031162-A1 | Mixed seasoning on basis of monosodium L-glutamate | AJINOMOTO CO., INC. (JP) | 1981-07-01 | — | — | EP | claimed |
| US-4258072-A | MSG, A 5'-NUCLEOTIDE, SUCCINIC ACID OR SODIUM SUCCINATE, SALT OF AN ORGANIC ACID | AJINOMOTO CO., INC. (JP) | 1981-03-24 | — | — | US | claimed |
| US-4180637-A | Process for the preparation of low molecular weight anhydride interpolymers | THE DOW CHEMICAL COMPANY (US) | 1979-12-25 | — | — | US | claimed |
| US-4162188-A | IN PRESENCE OF MALEIC ACID OR ITS SODIUM OR POTASSIUM SALT, MESACONIC ACID OR ITS SODIUM SALT, OR MALEIC ANHYDRIDE | HONSHU SEISHI KABUSHIKI KAISHA (JP) | 1979-07-24 | — | — | US | claimed |
| US-4141864-A | ORTHOPEDICS, DENTISTRY, IN SITU LEACHABLE PARTICLES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1979-02-27 | — | — | US | claimed |
| US-4061465-A | Creasable durable press textiles from methylol reagents and half amides or half salts of dicarboxylic acids | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-12-06 | — | — | US | claimed |
| US-4053612-A | FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-11 | — | — | US | claimed |
| US-4040970-A | WITH COPOLYMER FOR RENDERING THE TONER NEGATIVELY CHARGEABLE | CANON KABUSHIKI KAISHA (JA) | 1977-08-09 | — | — | US | claimed |
| US-3977983-A | Liquid developer for use in development of an electrostatic latent image comprising a copolymer containing an amino group converted into a quaternary ammonium salt or hydroxide | CANON KABUSHIKI KAISHA (JA) | 1976-08-31 | — | — | US | claimed |