Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279974 | 0.81 | ALDH1A1 (0.40) | BCHEACHEALDH1A1MEN1MAPK1 | |
| SCHEMBL5281014 | 0.79 | HDAC3 (0.49) | KMT2ASLC6A4 | |
| SCHEMBL5291953 | 0.79 | BCHE (0.44) | BCHEACHEALDH1A1HTR1A | |
| SCHEMBL5279163 | 0.79 | BCHE (0.50) | BCHEACHEALDH1A1MEN1MAPK1 | |
| SCHEMBL5283383 | 0.76 | ACHE (0.41) | BCHEACHEMEN1KMT2AHTR1A | |
| SCHEMBL5276908 | 0.73 | TACR1 (0.36) | MEN1KMT2ANPC1 | |
| SCHEMBL5279913 | 0.68 | BCHE (0.60) | BCHEACHEDRD2HTR1ASLC6A4 | |
| SCHEMBL5277140 | 0.67 | CCR1 (0.45) | BCHEACHEALDH1A1MEN1MAPK1 | |
| SCHEMBL6038039 | 0.67 | CCR1 (0.45) | BCHEACHEALDH1A1MEN1MAPK1 | |
| SCHEMBL5277138 | 0.67 | CCR1 (0.45) | BCHEACHEALDH1A1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | claimed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | claimed |