Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291953 | 0.95 | BCHE (0.44) | ACHEBCHEGFERCRHBPCRHR2 | |
| SCHEMBL5279974 | 0.84 | ALDH1A1 (0.40) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL5280809 | 0.83 | SIRT1 (0.47) | ACHEBCHEGFERMEN1KMT2A | |
| SCHEMBL5278312 | 0.82 | SIRT1 (0.46) | ACHEBCHEGFERMEN1KMT2A | |
| SCHEMBL5278902 | 0.79 | BCHE (0.47) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL5278446 | 0.78 | TACR1 (0.45) | ACHEBCHEMEN1KMT2AMAPT | |
| SCHEMBL5280164 | 0.76 | BCHE (0.43) | ACHEBCHEMEN1KMT2AHTR1A | |
| SCHEMBL5279163 | 0.75 | BCHE (0.50) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL5282667 | 0.73 | BCHE (0.55) | ACHEBCHEMEN1KMT2A | |
| SCHEMBL5282166 | 0.71 | ACHE (0.53) | ACHEBCHEMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | claimed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | claimed |