SCHEMBL528066

SCHEMBL528066

C=CC(=O)OC(F)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
CYP2C19 P33261 1/20 0.41
AKT1 P31749 1/20 0.39
CYP2D6 P10635 1/20 0.38
SRC P12931 1/20 0.38
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 1/20 0.36
TGM2 P21980 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439256 0.81 ESR1 (0.49) THRBHCAR2CYP2C19AKT1CYP2D6
SCHEMBL24708816 0.81 THRB (0.43) THRBHCAR2CYP2C19AKT1CYP2D6
SCHEMBL30881617 0.81 THRB (0.43) THRBHCAR2CYP2C19AKT1CYP2D6
SCHEMBL960203 0.79 THRB (0.42) THRBHCAR2CYP2C19AKT1CYP2D6
SCHEMBL25392381 0.79 HCAR2 (0.46) THRBHCAR2CYP2C19AKT1CYP2D6
SCHEMBL28387238 0.78 CYP2D6 (0.44) HCAR2CYP2D6SRCLMNAMAPK1
SCHEMBL28387237 0.78 CYP2D6 (0.44) HCAR2CYP2D6SRCLMNAMAPK1
SCHEMBL8364617 0.78 CYP2C19 (0.44) THRBHCAR2CYP2C19AKT1CYP2D6
SCHEMBL961211 0.78 THRB (0.41) THRBHCAR2CYP2C19AKT1CYP2D6
SCHEMBL299987 0.78 THRB (0.41) THRBHCAR2CYP2C19AKT1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 332 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146122-A1 POLYMERS MOLECULAR MEDICAL LTD (GB) 2026-05-28 US disclosed
US-12597609-B2 Positive electrode plate, secondary battery and power consuming device CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) 2026-04-07 US disclosed
EP-4594380-A1 POLYMERS Molecular Medical Ltd (GB) 2025-08-06 EP disclosed
EP-4280308-B1 POSITIVE ELECTRODE SHEET, SECONDARY BATTERY, AND ELECTRICAL APPARATUS CONTEMPORARY AMPEREX TECHNOLOGY HONG KONG LTD (HK) 2025-06-18 EP disclosed
EP-4503167-A1 POSITIVE ELECTRODE PLATE, SECONDARY BATTERY, AND ELECTRIC DEVICE Contemporary Amperex Technology Co., Limited (CN) 2025-02-05 EP disclosed
CN-119034812-A Catalyst composition, method for selectively hydrogenating conjugated diene latex, hydrogenated conjugated diene latex and application thereof 山东京博中聚新材料有限公司 2024-11-29 CN disclosed
US-20240396013-A1 POSITIVE ELECTRODE PLATE, SECONDARY BATTERY, AND ELECTRICAL APPARATUS CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) 2024-11-28 US disclosed
EP-3898707-B1 PROCESS FOR PRODUCING PEG ACRYLATE-HNBR COPOLYMER ARLANXEO DEUTSCHLAND GMBH (DE) 2024-09-18 EP disclosed
CN-116799151-B Positive electrode sheet, secondary battery and electricity utilization device 宁德时代新能源科技股份有限公司 2024-08-09 CN disclosed
CN-112004598-B Hydrogenation catalyst composition and use thereof for hydrogenating nitrile rubber 阿朗新科德国有限责任公司 2024-07-19 CN disclosed
EP-0704459-A1 Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition NIPPON ZEON CO., LTD. (JP) 1996-04-03 EP disclosed
EP-0704480-A1 Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber NIPPON ZEON CO., LTD. (JP) 1996-04-03 EP disclosed
US-5155190-A Suspension polymerization, excellent heat resistance, weatherproofing and transparency HITACHI CHEMICAL COMPANY (JP) 1992-10-13 US disclosed
US-RE34061-E And one or more unsaturated monomes; transparency, heat and moisture resistance optical elements HITACHI CHEMICAL CO., LTD. (JP) 1992-09-08 US disclosed
US-5013796-A Units of unsaturated nitrile, fluorine-containing vinyl monomer, conjugated diene, hydrogenated conjugated diene NIPPON ZEON CO., LTD. (JP) 1991-05-07 US disclosed
US-5013797-A Conjugated diene-acrylic ester-acrylic nitrile terpolymer; hydrogenated NIPPON ZEON CO., LTD. (JP) 1991-05-07 US disclosed
US-4956417-A UNSATURATED ESTER, CONJUGATED DIENE, HYDROGENATED CONJUGATED DIENES COPOLYMERS HAVING HEAT RESISTANCE AND OZONE RESISTANCE NIPPON ZEON CO., LTD. (JP) 1990-09-11 US disclosed
EP-0317263-A2 Optical material JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1989-05-24 EP disclosed
US-4591626-A TRANSPARENT OPTICAL MATERIALS HITACHI CHEMICAL COMPANY, LTD. (JP) 1986-05-27 US disclosed
EP-0141610-A2 Optical elements comprising polymers of (meth)acrylate esters Hitachi Chemical Co., Ltd. (JP) 1985-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12597609-B2 Positive electrode plate, secondary battery and power consuming device SCO2, CACNA2D4, CACNA2D1 THRB 1304/4885HCAR2 4834/4885CYP2C19 3704/4885
US-20260146122-A1 POLYMERS FGB, IPMK, PFKP THRB 466/4885HCAR2 403/4885CYP2C19 2912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.