Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365356 | 0.93 | CYP4F2 (0.49) | CYP4F2CYP4A11BAZ2BBAZ2ACYP1A2 | |
| SCHEMBL30998146 | 0.91 | CYP4F2 (0.50) | CYP4F2CYP4A11BAZ2BBAZ2ACYP1A2 | |
| SCHEMBL8335693 | 0.90 | CYP4F2 (0.53) | CYP4F2CYP4A11BAZ2BBAZ2ACYP1A2 | |
| SCHEMBL2549970 | 0.88 | LMNA (0.60) | CYP4F2CYP4A11BAZ2BBAZ2ACYP1A2 | |
| SCHEMBL364335 | 0.85 | TSHR (0.53) | LMNAMAPTTSHRGAACA1 | |
| SCHEMBL9573792 | 0.85 | ALDH1A1 (0.49) | CYP4F2CYP4A11BAZ2BBAZ2ACYP1A2 | |
| SCHEMBL9710977 | 0.85 | ALDH1A1 (0.49) | CYP4F2CYP4A11BAZ2BBAZ2ACYP1A2 | |
| SCHEMBL16962416 | 0.84 | BAZ2B (0.48) | CYP4F2CYP4A11BAZ2BBAZ2ACYP1A2 | |
| SCHEMBL366463 | 0.82 | TSHR (0.50) | LMNAMAPTSMN1; SMN2TSHRGAA | |
| SCHEMBL30680417 | 0.81 | ALDH1A1 (0.42) | CYP1A2CYP2C19LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791807-A1 | THERAPEUTIC DIPHENYL ETHER LIGANDS | Pfizer Products Incorporated (US) | 2007-06-06 | — | — | EP | disclosed |
| WO-2007010350-A1 | SYNTHESIS OF THERAPEUTIC DIPHENYL ETHERS | PFIZER PRODUCTS INC. (US) | 2007-01-25 | — | — | WO | disclosed |
| WO-2007010350-A1 | SYNTHESIS OF THERAPEUTIC DIPHENYL ETHERS | PFIZER PRODUCTS INC. (US) | 2007-01-25 | — | — | WO | disclosed |
| US-20070021634-A1 | SYNTHESIS OF THERAPEUTIC DIPHENYL ETHERS | PFIZER INC | 2007-01-25 | — | — | US | disclosed |
| US-20070021634-A1 | SYNTHESIS OF THERAPEUTIC DIPHENYL ETHERS | PFIZER INC | 2007-01-25 | — | — | US | disclosed |
| US-20070021634-A1 | SYNTHESIS OF THERAPEUTIC DIPHENYL ETHERS | PFIZER INC | 2007-01-25 | — | — | US | disclosed |
| WO-2006027684-A1 | THERAPEUTIC DIPHENYL ETHER LIGANDS | PFIZER PRODUCTS INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | PFIZER INC | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021634-A1 | SYNTHESIS OF THERAPEUTIC DIPHENYL ETHERS | DHFR, CYP2F1, EPOR | CYP4F2 7/4885CYP4A11 63/4885BAZ2B 1881/4885 |
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | HTR2B, HTR2C, HTR3B | CYP4F2 58/4885CYP4A11 36/4885BAZ2B 2110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.