SCHEMBL30998146

SCHEMBL30998146

CCOC(=O)c1cc(Cl)c(Cl)cc1F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
BAZ2B Q9UIF8 1/20 0.50
BAZ2A Q9UIF9 1/20 0.50
TSHR P16473 1/20 0.48
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA12 O43570 3/20 0.46
CA9 Q16790 3/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CA7 P43166 2/20 0.45
CA14 Q9ULX7 2/20 0.45
JMJD6 Q6NYC1 1/20 0.45
ALDH1A1 P00352 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280799 0.91 CYP4F2 (0.49) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL365356 0.91 CYP4F2 (0.49) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL9710977 0.87 ALDH1A1 (0.49) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL236240 0.87 CYP4F2 (0.57) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL2549970 0.86 LMNA (0.60) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL364335 0.83 TSHR (0.53) TSHRCA1CA2CA12CA9
SCHEMBL6732086 0.81 CYP4F2 (0.53) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL29923060 0.81 CYP4F2 (0.53) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL8335693 0.81 CYP4F2 (0.53) CYP4F2CYP4A11BAZ2BBAZ2ATSHR
SCHEMBL19971601 0.81 MAPK1 (0.52) CYP4F2CYP4A11BAZ2BBAZ2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024153856-A1 PROCESS FOR THE PREPARATION OF 3-(4,5-DICHLORO-2-(4-(TRIFLUOROMETHOXY)PHENOXY)BENZAMIDO)PYRIDINE 1-OXIDE ORION CORPORATION (FI) 2024-07-25 WO disclosed