Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528451 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL528906 | 0.89 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL528905 | 0.89 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL528034 | 0.88 | MMP2 (0.44) | ALDH1A1KMT2AMEN1MMP1MMP2 | |
| SCHEMBL528033 | 0.88 | MMP2 (0.44) | ALDH1A1KMT2AMEN1MMP1MMP2 | |
| SCHEMBL528379 | 0.85 | KMT2A (0.40) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL531077 | 0.81 | GPR139 (0.40) | ALDH1A1KMT2AMEN1KDM4EGPR139 | |
| SCHEMBL531078 | 0.81 | GPR139 (0.40) | ALDH1A1KMT2AMEN1KDM4EGPR139 | |
| SCHEMBL15377187 | 0.78 | KMT2A (0.48) | ALDH1A1KMT2AMEN1KDM4EGPR139 | |
| SCHEMBL1843672 | 0.78 | KMT2A (0.48) | ALDH1A1KMT2AMEN1KDM4EGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598493-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012014114-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |