Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL218538 | 0.73 | TSHR (0.36) | TSHRPTPN1ALDH1A1ACHE | |
| SCHEMBL13143012 | 0.71 | TSHR (0.35) | TSHRPTPN1ALDH1A1ACHELMNA | |
| SCHEMBL9091284 | 0.71 | — | — | |
| SCHEMBL9730908 | 0.69 | — | — | |
| SCHEMBL7137575 | 0.69 | — | — | |
| SCHEMBL7235362 | 0.69 | ALDH1A1 (0.33) | TSHRPTPN1ALDH1A1ACHESMN1; SMN2 | |
| SCHEMBL5964898 | 0.69 | TSHR (0.43) | TSHRPTPN1ALDH1A1HTTCRHBP | |
| SCHEMBL125009 | 0.68 | ACHE (0.32) | TSHRALDH1A1CRHBPCRHR2ACHE | |
| SCHEMBL7237915 | 0.68 | PTPN1 (0.35) | TSHRPTPN1ACHELMNAL3MBTL1 | |
| SCHEMBL125436 | 0.68 | POLB (0.39) | TSHRALDH1A1HTTACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199542-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | BAYER AKTIENGESELLSCHAFT (DE) | 2024-06-20 | — | — | US | claimed |
| CN-117043140-A | Substituted pyrrolidin-2-ones, salts thereof and their use as herbicidal active substances | 拜耳公司 | 2023-11-10 | — | — | CN | claimed |
| EP-0879054-B1 | APPLICATION OF PYRROLIDINE DERIVATIVES TO THE PREPARATION OF MEDICAMENTS INTENDED TO THE TREATMENT OF DRUG ABUSE | AVENTIS PHARMA SA (FR) | 2007-11-28 | — | — | EP | claimed |
| WO-2003031420-A1 | ISOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-0828486-B1 | USE OF PYRROLIDINE DERIVATIVES FOR TREATING ALCOHOLISM | AVENTIS PHARMA SA (FR) | 2002-09-18 | — | — | EP | claimed |
| US-6150387-A | Heterocyclic carboxamide compounds effective in the treatment of drug abuse | RHONE-POULENC RORER S.A. (FR) | 2000-11-21 | — | — | US | claimed |
| US-5935980-A | Use of pyrrolidine derivatives in the treatment of alcoholism | RHONE-POULENC RORER S.A. (FR) | 1999-08-10 | — | — | US | claimed |
| EP-0766696-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1998-09-02 | — | — | EP | claimed |
| EP-0766695-B1 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF CHOLECYSTOKININE AND GASTRINE-RELATED DISORDERS | RHONE POULENC RORER SA (FR) | 1998-07-22 | — | — | EP | claimed |
| EP-0679161-B1 | THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1998-06-24 | — | — | EP | claimed |
| US-5624939-A | N-acyl pyrrolidines and drugs for the treatment or prevention of cholecystokinin and gastrin-related disorders | RHONE-POULENC RORER, S.A. (FR) | 1997-04-29 | — | — | US | claimed |
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | claimed |
| EP-0678088-B1 | N-ACYL PYRROLIDINES AND DRUGS FOR THE TREATMENT OR PREVENTION OF CHOLECYSTOKININ AND GASTRIN-RELATED DISORDERS | RHONE POULENC RORER SA (FR) | 1996-10-09 | — | — | EP | claimed |
| EP-0678089-B1 | N-ACYL PYRROLIDINES AND DRUGS FOR THE TREATMENT OR PREVENTION OF CHOLECYSTOKININ AND GASTRIN-RELATED DISORDERS | RHONE POULENC RORER SA (FR) | 1996-10-09 | — | — | EP | claimed |
| EP-0593639-B1 | PYRROLIDINE AND THIAZOLIDINE DERIVATIVES, PREPARATION THEREOF AND DRUGS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1995-04-05 | — | — | EP | claimed |
| US-5270308-A | Hypotensives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-12-14 | — | — | US | claimed |
| EP-0417555-B1 | Pentamethine dyes and derivatives | BAYER AG (DE) | 1993-11-03 | — | — | EP | claimed |
| US-5118814-A | Pressure sensitive and heat sensitive recording media | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| EP-0417555-A1 | Pentamethine dyes and derivatives | BAYER AG (DE) | 1991-03-20 | — | — | EP | claimed |
| EP-0370198-A1 | Tetraindolyl heptamethine derivatives | BAYER AG (DE) | 1990-05-30 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199542-A1 | SUBSTITUTED PYRROLIDIN-2-ONES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | HPD, DDT, PPOX | TSHR 1754/4885PTPN1 372/4885ALDH1A1 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.