Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291190 | 0.87 | ACHE (0.50) | ALDH1A1ACHELMNASMN1; SMN2GAA | |
| SCHEMBL542640 | 0.87 | ACHE (0.58) | ALDH1A1ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9886769 | 0.82 | ALDH1A1 (0.68) | ALDH1A1ACHESMN1; SMN2GAAHTT | |
| SCHEMBL5284823 | 0.81 | ACHE (0.41) | ALDH1A1ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5292439 | 0.81 | NPC1 (0.42) | ALDH1A1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL24086431 | 0.80 | ACHE (0.59) | ALDH1A1ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5281805 | 0.78 | DRD2 (0.55) | SMN1; SMN2TDP1L3MBTL1ADRB2ADRB1 | |
| SCHEMBL12006 | 0.75 | LMNA (0.59) | ALDH1A1ACHESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5283288 | 0.75 | ACHE (0.44) | ALDH1A1ACHELMNASMN1; SMN2MRGPRX4 | |
| SCHEMBL16981249 | 0.74 | ACHE (0.47) | ALDH1A1ACHELMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006138653-A9 | THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME | NASHUA CORP (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2006138653-A1 | THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME | NASHUA CORPORATION (US) | 2006-12-28 | — | — | WO | disclosed |