Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528599 | 0.92 | MAPT (0.51) | ALDH1A1MAPTHPGDKDM4EPOLB | |
| SCHEMBL528658 | 0.91 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDKDM4EPOLB | |
| SCHEMBL529730 | 0.91 | MAPT (0.58) | ALDH1A1MAPTHPGDKDM4EPOLB | |
| SCHEMBL528340 | 0.90 | FFAR1 (0.51) | ALDH1A1MAPTHPGDKDM4EFFAR1 | |
| SCHEMBL528847 | 0.89 | MEN1 (0.55) | ALDH1A1MAPTHPGDKDM4EPOLB | |
| SCHEMBL528468 | 0.89 | L3MBTL1 (0.57) | ALDH1A1MAPTHPGDKDM4EPOLB | |
| SCHEMBL528702 | 0.89 | MAPT (0.58) | ALDH1A1MAPTHPGDKDM4EFFAR1 | |
| SCHEMBL528331 | 0.89 | FFAR1 (0.49) | ALDH1A1MAPTHPGDKDM4EFFAR1 | |
| SCHEMBL529037 | 0.88 | MAPT (0.51) | ALDH1A1MAPTHPGDKDM4EPOLB | |
| SCHEMBL529287 | 0.88 | KMT2A (0.64) | ALDH1A1MAPTHPGDKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |