Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SMO | Q99835 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528672 | 0.91 | SMO (0.46) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL528200 | 0.91 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528301 | 0.90 | MAPT (0.48) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528589 | 0.90 | MEN1 (0.52) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL527865 | 0.90 | SMO (0.47) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL529639 | 0.89 | MAPT (0.55) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528022 | 0.89 | LMNA (0.49) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL529730 | 0.88 | MAPT (0.58) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528599 | 0.87 | MAPT (0.51) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL529590 | 0.87 | LMNA (0.49) | ALDH1A1MAPTKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |