Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037988 | 0.84 | MMP1 (0.51) | MAPTMEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL5277895 | 0.76 | CYP2C9 (0.58) | MAPTMEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL1695076 | 0.76 | SMN1; SMN2 (0.66) | MAPTMEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL6038318 | 0.76 | HDAC3 (0.58) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL20303790 | 0.75 | MAPT (0.61) | MAPTMEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL152811 | 0.74 | KMT2A (0.74) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL15306496 | 0.73 | CNR1 (0.77) | MAPTMEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL15306499 | 0.73 | CNR1 (0.77) | MAPTMEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL1395699 | 0.73 | CNR1 (0.60) | MAPTMEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL20718868 | 0.73 | ALDH1A1 (0.60) | MAPTMEN1KMT2ACNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |