Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5274739 | 0.98 | MMP2 (0.51) | MMP2MMP9MMP8MMP13SIGMAR1 | |
| SCHEMBL5274927 | 0.95 | MMP2 (0.43) | MMP2MMP9MMP8MMP13SIGMAR1 | |
| SCHEMBL5275325 | 0.87 | MMP2 (0.38) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL5280214 | 0.80 | TP53 (0.41) | MMP2MMP9MMP8MMP13TP53 | |
| SCHEMBL5438308 | 0.76 | L3MBTL1 (0.42) | SIGMAR1MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL5277353 | 0.74 | TSHR (0.37) | DNM1SMN1; SMN2GAA | |
| SCHEMBL5280463 | 0.73 | MMP2 (0.46) | MMP2MMP9MMP8MMP13MEN1 | |
| SCHEMBL5280457 | 0.72 | TSHR (0.35) | — | |
| SCHEMBL5282819 | 0.72 | TSHR (0.42) | DNM1MEN1KMT2A | |
| SCHEMBL6002827 | 0.72 | ALDH1A1 (0.39) | SMN1; SMN2MAPK1ALOX12HTTKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |