Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282506 | 0.87 | MAOB (0.43) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL6002831 | 0.79 | TSHR (0.41) | ALDH1A1HPGDMAOAMAOBTDP1 | |
| SCHEMBL10967375 | 0.79 | MAOA (0.38) | ALDH1A1MAOAMAOBLOXL2CALM1 | |
| SCHEMBL5280214 | 0.79 | TP53 (0.41) | ALDH1A1MAOAMAOBELANENPSR1 | |
| SCHEMBL5275325 | 0.76 | MMP2 (0.38) | ALDH1A1HPGDHSD17B10MAOAMAOB | |
| SCHEMBL5279760 | 0.75 | SLC6A2 (0.35) | HPGDMAOAMAOBELANETAAR1 | |
| SCHEMBL5278439 | 0.75 | TAAR1 (0.35) | ALDH1A1MAOAMAOBELANECYP2A6 | |
| SCHEMBL5284942 | 0.74 | MAOA (0.40) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL5282068 | 0.72 | MMP2 (0.49) | ALOX12SMN1; SMN2KCNH2HTTMAPK1 | |
| SCHEMBL5274739 | 0.71 | MMP2 (0.51) | ALOX12SMN1; SMN2KCNH2HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |