Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | AGXT | P21549 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4795297 | 0.77 | MAOA (0.40) | OPRL1OPRM1OPRK1MAOAMAOB | |
| SCHEMBL5282506 | 0.76 | MAOB (0.43) | MAOAMAOBCALM1IDO1TSHR | |
| SCHEMBL2233425 | 0.74 | MAOA (0.32) | MAOAMAOBP2RX1P2RX3P2RX4 | |
| SCHEMBL3925565 | 0.74 | GAA (0.41) | OPRL1OPRM1MAOAMAOBP2RX1 | |
| SCHEMBL5285392 | 0.74 | TSHR (0.37) | OPRL1OPRM1OPRK1TSHRTP53 | |
| SCHEMBL9978691 | 0.73 | MAOB (0.40) | MAOAMAOBCALM1IDO1TSHR | |
| SCHEMBL5278331 | 0.73 | MAOA (0.40) | MAOAMAOBCALM1IDO1TSHR | |
| SCHEMBL22032520 | 0.73 | MAOA (0.40) | MAOAMAOBCALM1IDO1TSHR | |
| SCHEMBL5274344 | 0.73 | MAOA (0.40) | MAOAMAOBCALM1CYP3A4IDO1 | |
| SCHEMBL5284942 | 0.73 | MAOA (0.40) | MAOAMAOBCALM1IDO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |