Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5275530 | 0.82 | KDM4E (0.35) | TSHRMEN1POLBKMT2ACYP1A2 | |
| SCHEMBL5279220 | 0.79 | OPRM1 (0.44) | TSHRKDM4EGAAALDH1A1HPGD | |
| SCHEMBL5280463 | 0.77 | MMP2 (0.46) | MEN1KMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL3925565 | 0.76 | GAA (0.41) | TSHRPOLBKMT2ATDP1LMNA | |
| SCHEMBL2233425 | 0.76 | MAOA (0.32) | — | |
| SCHEMBL18788061 | 0.76 | TSHR (0.37) | TSHRMEN1POLBKMT2ACYP1A2 | |
| SCHEMBL5275494 | 0.76 | OPRM1 (0.32) | POLBALDH1A1OPRM1OPRK1OPRL1 | |
| SCHEMBL5280180 | 0.76 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1OPRM1OPRK1 | |
| SCHEMBL6002542 | 0.76 | LMNA (0.33) | MEN1POLBKMT2ALMNAOPRM1 | |
| SCHEMBL5276415 | 0.76 | MMP2 (0.49) | MEN1KMT2AKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |