Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002831 | 0.87 | TSHR (0.41) | MAOBMAOACALM1TSHRALDH1A1 | |
| SCHEMBL6002827 | 0.87 | ALDH1A1 (0.39) | MAOBMAOACALM1ALDH1A1LOXL2 | |
| SCHEMBL10967375 | 0.87 | MAOA (0.38) | MAOBMAOACALM1TSHRALDH1A1 | |
| SCHEMBL5280214 | 0.87 | TP53 (0.41) | MAOBMAOACALM1TSHRALDH1A1 | |
| SCHEMBL5275325 | 0.83 | MMP2 (0.38) | MAOBMAOACALM1ALDH1A1TP53 | |
| SCHEMBL5278439 | 0.82 | TAAR1 (0.35) | MAOBMAOAALDH1A1TP53TRPA1 | |
| SCHEMBL5279760 | 0.82 | SLC6A2 (0.35) | MAOBMAOATSHRTP53TRPA1 | |
| SCHEMBL5282068 | 0.79 | MMP2 (0.49) | TP53ALOX12 | |
| SCHEMBL5274739 | 0.78 | MMP2 (0.51) | TP53ALOX12 | |
| SCHEMBL5278331 | 0.76 | MAOA (0.40) | MAOBMAOACALM1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |