Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282506 | 0.76 | MAOB (0.43) | MAOAMAOBALDH1A1HPGDALOX15 | |
| SCHEMBL6002827 | 0.74 | ALDH1A1 (0.39) | MAOAMAOBALDH1A1HPGDALOX15 | |
| SCHEMBL5282094 | 0.73 | OPRL1 (0.42) | MAOAMAOBALDH1A1CALM1KDM1A | |
| SCHEMBL5274344 | 0.73 | MAOA (0.40) | MAOAMAOBALDH1A1HPGDCALM1 | |
| SCHEMBL5282457 | 0.73 | MAOA (0.40) | MAOAMAOBALDH1A1CALM1KDM1A | |
| SCHEMBL3034490 | 0.73 | MAOA (0.40) | MAOAMAOBALDH1A1CALM1KDM1A | |
| SCHEMBL5277481 | 0.73 | ELANE (0.40) | MAOAMAOBCALM1TSHRTP53 | |
| SCHEMBL5278331 | 0.73 | MAOA (0.40) | MAOAMAOBALDH1A1CALM1KDM1A | |
| SCHEMBL22032520 | 0.73 | MAOA (0.40) | MAOAMAOBALDH1A1HSD17B10CALM1 | |
| SCHEMBL9978691 | 0.73 | MAOB (0.40) | MAOAMAOBALDH1A1HSD17B10CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |