SCHEMBL5282333

SCHEMBL5282333

Cc1csc(CCC(=O)Oc2c(F)c(F)c(F)c(F)c2F)c1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.34
KDM4C Q9H3R0 1/20 0.32
FFAR1 O14842 1/20 0.31
KMT2A Q03164 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5289722 0.85 DAO (0.36) DAOKDM4CKMT2AKDM4ELMNA
SCHEMBL3939509 0.80 RPS6KB2 (0.42) DAOKDM4CKMT2ALMNAHTT
SCHEMBL5279684 0.75 NPC1 (0.49) DAOKMT2ALMNAMAPK1HTT
SCHEMBL2399697 0.74 DAO (0.47) DAOKDM4CFFAR1KDM4E
SCHEMBL8855371 0.74 DAO (0.42) DAOKDM4CFFAR1KDM4ELMNA
SCHEMBL8540112 0.73 DAO (0.41) DAOKDM4CFFAR1KMT2ALMNA
SCHEMBL7354171 0.71 IAPP (0.41) DAOKDM4CFFAR1KMT2ALMNA
SCHEMBL8003191 0.71 KMT2A (0.41) KMT2ALMNAHTTL3MBTL1
SCHEMBL5285647 0.71 ALOX5 (0.40) KDM4CFFAR1KMT2AKDM4ELMNA
SCHEMBL5285884 0.70 DAO (0.52) DAOKMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007001335-A2 RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY VICURON PHARMACEUTICALS INC. (US) 2007-01-04 WO disclosed
US-20060211603-A1 Ramoplanin derivatives possessing antibacterial activity VICURON PHARMACEUTICALS INC. (US) 2006-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060211603-A1 Ramoplanin derivatives possessing antibacterial activity CLSPN, LMAN2, RPN2 DAO 1438/4885KDM4C 4288/4885FFAR1 4682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.