Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12762242 | 0.91 | TSHR (0.56) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL23813740 | 0.91 | ALDH1A1 (0.43) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL13705616 | 0.91 | EGLN1 (0.43) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL17337909 | 0.90 | KMT2A (0.48) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL4953772 | 0.90 | KMT2A (0.44) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL21049231 | 0.88 | KMT2A (0.43) | KMT2AMAPTALDH1A1LMNATSHR | |
| SCHEMBL1401783 | 0.88 | ALDH1A1 (0.48) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL14968457 | 0.88 | VCAM1 (0.41) | KMT2AMAPTALDH1A1LMNAHTT | |
| SCHEMBL25495837 | 0.88 | KMT2A (0.43) | KMT2AMAPTALDH1A1LMNATSHR | |
| SCHEMBL522462 | 0.88 | KMT2A (0.43) | KMT2AMAPTALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240165259-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-23 | — | — | US | disclosed |
| EP-4320073-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | Dana-Farber Cancer Institute, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-117337267-A | Bioorthogonal reactions suitable for click/click cancellation applications | 达纳－法伯癌症研究所公司 | 2024-01-02 | — | — | CN | disclosed |
| US-6297216-B1 | ADMINISTERING A DIPEPTIDE DERIVATIVE TO MAMMALS | SOLVO BIOTECHNOLOGY (HU) | 2001-10-02 | — | — | US | disclosed |
| EP-0770091-B1 | COMPOUNDS FOR REVERSING DRUG RESISTANCE | SARKADI BALAZS (HU) | 2000-03-01 | — | — | EP | disclosed |
| EP-0770091-A1 | COMPOUNDS FOR REVERSING DRUG RESISTANCE | Sarkadi, Balazs (HU) | 1997-05-02 | — | — | EP | disclosed |
| WO-1995031474-A1 | COMPOUNDS FOR REVERSING DRUG RESISTANCE | SARKADI BALAZS (HU) | 1995-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240165259-A1 | BIOORTHOGONAL REACTION SUITABLE FOR CLICK/UNCLICK APPLICATIONS | CILK1, SYMPK, DCK | KMT2A 3829/4885MAPT 3211/4885ALDH1A1 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.