Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | CTSH | P09668 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620409 | 0.82 | CTSK (0.40) | CTSKCTSSCTSLCTSBCTSH | |
| Hydrochloric Acid SCHEMBL7838394 | 0.79 | METAP1 (0.41) | CTSKCTSSMETAP1 | |
| SCHEMBL24599801 | 0.76 | CYP1A2 (0.39) | CTSKCTSLCTSBCTSH | |
| SCHEMBL27601913 | 0.73 | LTA4H (0.39) | CTSKCTSSCTSLCTSBCTSH | |
| SCHEMBL7794348 | 0.72 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL5326239 | 0.72 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL19817250 | 0.72 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL14947101 | 0.72 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL28948946 | 0.72 | LTA4H (0.46) | CTSKCTSLCTSBLTA4H | |
| SCHEMBL13423682 | 0.72 | LTA4H (0.40) | CTSKCTSSCTSLCTSBCTSH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145570-B2 | Enzymatic acylation method using an acylphosphonate donor | PCAS BIOSOLUTION (FR) | 2015-09-29 | — | — | US | disclosed |
| EP-2598644-A1 | ENZYMATIC ACYLATION METHOD USING AN ACYLPHOSPHONATE DONOR | PCAS Biosolution (FR) | 2013-06-05 | — | — | EP | disclosed |
| US-20130130337-A1 | Enzymatic Acylation Method Using an Acylphosphonate Donor | PCAS BIOSOLUTION (FR) | 2013-05-23 | — | — | US | disclosed |
| WO-2012013765-A1 | ENZYMATIC ACYLATION METHOD USING AN ACYLPHOSPHONATE DONOR | PCAS BIOSOLUTION (FR) | 2012-02-02 | — | — | WO | disclosed |