Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27644007 | 0.85 | METAP1 (0.44) | GRM2GRM3 | |
| SCHEMBL528247 | 0.82 | CTSK (0.42) | CTSKCTSSCTSLCTSBLTA4H | |
| SCHEMBL27601913 | 0.77 | LTA4H (0.39) | CTSKCTSSGRM2GRM3DPP4 | |
| SCHEMBL27620473 | 0.75 | LTA4H (0.37) | CTSKCTSSGRM2GRM3DPP4 | |
| SCHEMBL27620521 | 0.74 | GGT1 (0.38) | CTSKCTSSGRM2GRM3CTSL | |
| SCHEMBL27644133 | 0.73 | ALDH1A1 (0.41) | GRM2GRM3DPP4 | |
| SCHEMBL24599801 | 0.73 | CYP1A2 (0.39) | CTSKCTSLCTSBCTSH | |
| SCHEMBL28758252 | 0.73 | EPHX1 (0.41) | GRM2GRM3DPP4 | |
| Hydrochloric Acid SCHEMBL7838392 | 0.72 | CPB2 (0.38) | CTSKCTSSGRM2GRM3DPP4 | |
| Hydrochloric Acid SCHEMBL7838394 | 0.72 | METAP1 (0.41) | CTSKCTSSGRM2GRM3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | claimed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | claimed |
| CN-1886363-A | Amino acids with affinity for the alpha2delta-protein | WARNER LAMBERT CO (US) | 2006-12-27 | — | — | CN | disclosed |