SCHEMBL5282494

SCHEMBL5282494

Cc1c(N)cc2c(c1N(C)C)C(c1ccccc1Cl)c1ccccc1O2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
AHR P35869 2/20 0.33
CDK1 P06493 1/20 0.33
ROS1 P08922 1/20 0.33
MARK3 P27448 1/20 0.33
CLK2 P49760 1/20 0.33
GSK3B P49841 1/20 0.33
LIMK1 P53667 1/20 0.33
CDK5 Q00535 1/20 0.33
SLK Q9H2G2 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
MAP4K5 Q9Y4K4 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
HTR2A P28223 5/20 0.32
HTR2C P28335 5/20 0.32
ADRA2A P08913 3/20 0.32
DRD2 P14416 3/20 0.32
ADRA2C P18825 3/20 0.32
DRD1 P21728 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5501565 0.74 AHR (0.40) MEN1KMT2AAHRCDK1ROS1
SCHEMBL80832 0.70 MAPT (0.42) MEN1KMT2AAHRCDK1ROS1
SCHEMBL3896874 0.68 LMNA (0.46) MEN1KMT2AAHRHTR2AHTR2C
SCHEMBL5501554 0.66 MEN1 (0.40) MEN1KMT2AAHRHTR2AHTR2C
SCHEMBL11594463 0.62 MEN1 (0.45) MEN1KMT2AAHRTAAR1HTR2A
SCHEMBL1524420 0.61 CYP2C9 (0.51) MEN1KMT2AAHRHTR2AHTR2C
SCHEMBL9407337 0.60 AHR (0.46) MEN1KMT2AAHRHTR2AHTR2C
SCHEMBL3907415 0.60 MEN1 (0.44) MEN1KMT2ATAAR1GHSRCYP2C9
SCHEMBL11572801 0.59 MAOA (0.42) MEN1KMT2AHTR2AHTR2CHRH1
SCHEMBL30552229 0.59 CYP2C9 (0.52) MEN1KMT2ATAAR1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1602480-B1 Method for colored image formation FUJIFILM CORP (JP) 2007-12-12 EP disclosed