Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8258456 | 0.89 | IDO1 (0.42) | MMP9MMP8IDO1NPBWR1KDM4E | |
| SCHEMBL6038167 | 0.85 | MMP9 (0.40) | MMP9MMP8IDO1KDM4EHPGD | |
| SCHEMBL5283297 | 0.84 | IDO1 (0.38) | MMP9MMP8IDO1NPBWR1KDM4E | |
| SCHEMBL30023820 | 0.77 | MMP9 (0.46) | MMP9MMP8KDM4EHPGDHSD17B10 | |
| SCHEMBL18395376 | 0.77 | MMP9 (0.46) | MMP9MMP8KDM4EHPGDHSD17B10 | |
| SCHEMBL5283086 | 0.77 | IDO1 (0.59) | MMP9MMP8IDO1KDM4E | |
| SCHEMBL5283091 | 0.77 | IDO1 (0.59) | MMP9MMP8IDO1KDM4E | |
| Hydrochloric Acid SCHEMBL18395638 | 0.76 | MMP9 (0.46) | MMP9MMP8KDM4EHPGDHSD17B10 | |
| SCHEMBL5283128 | 0.76 | ALDH1A1 (0.46) | MMP9MMP8KDM4EHPGDHSD17B10 | |
| SCHEMBL6037979 | 0.76 | ALDH1A1 (0.46) | MMP9MMP8KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |