Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | NMBR | P28336 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282628 | 0.89 | MMP9 (0.43) | IDO1MMP9MMP8CNR2NPBWR1 | |
| SCHEMBL6038167 | 0.80 | MMP9 (0.40) | IDO1MMP9MMP8KDM4EHPGD | |
| SCHEMBL5283091 | 0.79 | IDO1 (0.59) | IDO1MMP9MMP8KDM4E | |
| SCHEMBL5283086 | 0.79 | IDO1 (0.59) | IDO1MMP9MMP8KDM4E | |
| SCHEMBL5283297 | 0.74 | IDO1 (0.38) | IDO1MMP9MMP8NPBWR1KDM4E | |
| SCHEMBL6037979 | 0.73 | ALDH1A1 (0.46) | MMP9MMP8ALDH1A1KDM4EHPGD | |
| SCHEMBL5283128 | 0.73 | ALDH1A1 (0.46) | MMP9MMP8ALDH1A1KDM4EHPGD | |
| SCHEMBL30023820 | 0.72 | MMP9 (0.46) | MMP9MMP8CNR2ALDH1A1KDM4E | |
| SCHEMBL18395376 | 0.72 | MMP9 (0.46) | MMP9MMP8CNR2ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL18395638 | 0.71 | MMP9 (0.46) | MMP9MMP8CNR2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |