Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5302367 | 0.93 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1KDM4ENPSR1KMT2A | |
| SCHEMBL5287647 | 0.91 | KMT2A (0.49) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL5301204 | 0.83 | KMT2A (0.49) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5295936 | 0.83 | MAPT (0.41) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2291392 | 0.82 | KMT2A (0.51) | ALDH1A1L3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL2295674 | 0.81 | NPC1 (0.56) | ALDH1A1L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5294218 | 0.81 | RAB9A (0.45) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2296670 | 0.80 | NR1I2 (0.47) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2296252 | 0.80 | NR1I2 (0.47) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5281598 | 0.80 | GAA (0.46) | ALDH1A1KMT2AMEN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828144-A2 | INTEGRIN ANTAGONISTS USEFUL AS ANTICANCER AGENTS | OSI Pharmaceuticals, Inc. (US) | 2007-09-05 | — | — | EP | claimed |
| WO-2006053342-A2 | INTEGRIN ANTAGONISTS USEFUL AS ANTICANCER AGENTS | OSI PHARMACEUTICALS, INC. (US) | 2006-05-18 | — | — | WO | claimed |