Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748342 | 0.87 | SMN1; SMN2 (0.52) | MAPTLMNARECQLPOLBBLM | |
| SCHEMBL1748256 | 0.84 | HTR6 (0.54) | MAPTLMNARECQLPOLBBLM | |
| Hydrochloric Acid SCHEMBL1748665 | 0.83 | HTR6 (0.53) | MAPTLMNARECQLPOLBBLM | |
| SCHEMBL5280148 | 0.78 | ACLY (0.43) | MAPTLMNARECQLPOLBHTT | |
| Tert-Butyl Formate SCHEMBL27915001 | 0.77 | HTR6 (0.49) | MAPTLMNARECQLPOLBBLM | |
| SCHEMBL1748293 | 0.72 | ADRA1A (0.54) | ADRA2CADRA1DADRA1AADRA1BACLY | |
| SCHEMBL21295182 | 0.71 | KCNQ2 (0.43) | LMNACYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7048785 | 0.71 | HTR6 (0.72) | MAPTHTR6ALDH1A1NPSR1MAPK1 | |
| SCHEMBL1748702 | 0.70 | SMN1; SMN2 (0.50) | MAPTLMNAHTTCYP2C19ENPP2 | |
| SCHEMBL5021177 | 0.70 | HTR6 (0.59) | MAPTLMNARECQLPOLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856075-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND THEIR USE AS 5-HT6 MODULATORS | Epix Delaware, Inc. (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006081332-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND THEIR USE AS 5-HT6 MODULATORS | EPIX DELAWARE, INC. (US) | 2006-08-03 | — | — | WO | disclosed |