Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 4/20 | 0.36 |
| ▸ | MMP8 | P22894 | 4/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21352446 | 0.80 | LMNA (0.40) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL21352435 | 0.78 | LMNA (0.38) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL21352442 | 0.78 | LMNA (0.38) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL21352448 | 0.78 | LMNA (0.38) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL21352441 | 0.78 | LMNA (0.38) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL8667553 | 0.76 | LMNA (0.35) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL527315 | 0.71 | MMP2 (0.37) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL2991776 | 0.71 | LMNA (0.33) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL7646205 | 0.71 | MMP1 (0.37) | LMNACYP1A2PKMPTK2BFDPS | |
| SCHEMBL23795092 | 0.71 | LMNA (0.32) | LMNAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145570-B2 | Enzymatic acylation method using an acylphosphonate donor | PCAS BIOSOLUTION (FR) | 2015-09-29 | — | — | US | claimed |
| EP-2598644-A1 | ENZYMATIC ACYLATION METHOD USING AN ACYLPHOSPHONATE DONOR | PCAS Biosolution (FR) | 2013-06-05 | — | — | EP | claimed |
| US-20130130337-A1 | Enzymatic Acylation Method Using an Acylphosphonate Donor | PCAS BIOSOLUTION (FR) | 2013-05-23 | — | — | US | claimed |
| WO-2012013765-A1 | ENZYMATIC ACYLATION METHOD USING AN ACYLPHOSPHONATE DONOR | PCAS BIOSOLUTION (FR) | 2012-02-02 | — | — | WO | claimed |
| WO-2023233376-A1 | FOAM COMPOSITION INCLUDING SURFACE-MODIFIED NANOPARTICLES AND RELATED ARTICLES AND PROCESSES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2023-12-07 | — | — | WO | disclosed |
| US-9145570-B2 | Enzymatic acylation method using an acylphosphonate donor | PCAS BIOSOLUTION (FR) | 2015-09-29 | — | — | US | disclosed |
| EP-2598644-A1 | ENZYMATIC ACYLATION METHOD USING AN ACYLPHOSPHONATE DONOR | PCAS Biosolution (FR) | 2013-06-05 | — | — | EP | disclosed |
| US-20130130337-A1 | Enzymatic Acylation Method Using an Acylphosphonate Donor | PCAS BIOSOLUTION (FR) | 2013-05-23 | — | — | US | disclosed |
| WO-2012013765-A1 | ENZYMATIC ACYLATION METHOD USING AN ACYLPHOSPHONATE DONOR | PCAS BIOSOLUTION (FR) | 2012-02-02 | — | — | WO | disclosed |
| EP-1419182-B1 | IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE | BRIDGESTONE CORP (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-1419182-A1 | IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| WO-2004018462-A1 | QUINAZOLINONE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |
| US-6610804-B2 | An iron compound, an alpha-acylphosphonate diester, and an organoaluminum compound | BRIDGESTONE CORPORATION (JP) | 2003-08-26 | — | — | US | disclosed |
| US-6576725-B1 | Iron compound, organomagnesium compound, and alpha-acylphosphonate diester; addition polymerization | BRIDGESTONE CORPORATION (JP) | 2003-06-10 | — | — | US | disclosed |
| US-20030073790-A1 | Iron-based catalyst composition for the manufacture of syndiotactic 1, 2-polybutadiene | BRIDGESTONE CORP. | 2003-04-17 | — | — | US | disclosed |
| US-20030073570-A1 | Method of preparing oligomers of conjugated dienes with an iron-based catalyst composition | BRIDGESTONE CORP. | 2003-04-17 | — | — | US | disclosed |
| WO-2003018644-A1 | IRON-BASED CATALYST COMPOSITION FOR THE MANUFACTURE OF SYNDIOTACTIC 1,2-POLYBUTADIENE | BRIDGESTONE CORPORATION (JP) | 2003-03-06 | — | — | WO | disclosed |
| US-5656709-A | Hybrid material and process for producing the same | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 1997-08-12 | — | — | US | disclosed |
| US-4324744-A | PHOTOINITIATORS | BASF AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |