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SCHEMBL8667553

SCHEMBL8667553

CC(C)(C)C(=O)P(=O)(C(=O)C(C)(C)C)C(=O)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.35
▸ FDPS P14324 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ CYP1A2 P05177 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ PTK2B Q14289 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL528357 0.76 LMNA (0.40) LMNAFDPSALDH1A1TSHRCYP1A2
SCHEMBL21352446 0.76 LMNA (0.40) LMNAFDPSALDH1A1TSHRCYP1A2
SCHEMBL21352442 0.73 LMNA (0.38) LMNAFDPSCYP1A2PKMPTK2B
SCHEMBL21352441 0.73 LMNA (0.38) LMNAFDPSCYP1A2PKMPTK2B
SCHEMBL28676633 0.73 CYP1A2 (0.33) LMNAFDPSCYP1A2PKMPTK2B
SCHEMBL23795092 0.73 LMNA (0.32) LMNAFDPS
SCHEMBL21352435 0.73 LMNA (0.38) LMNAFDPSCYP1A2PKMPTK2B
SCHEMBL21352448 0.73 LMNA (0.38) LMNAFDPSCYP1A2PKMPTK2B
SCHEMBL155530 0.69 L3MBTL1 (0.33) LMNA
SCHEMBL8669658 0.69 ALDH1A1 (0.30) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779891-B1 NOVEL ACYLPHOSPHINE OXIDES CIBA GEIGY AG (CH) 1998-12-23 — — EP disclosed
US-5721292-A PHOTOPOLYMERIZATION INITIATOR CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-02-24 — — US disclosed