Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14003500 | 0.86 | MAPT (0.57) | HTTMAPTHSP90AA1NPSR1LMNA | |
| SCHEMBL527995 | 0.84 | PARP1 (0.56) | HTTPARP1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL29706670 | 0.84 | LMNA (0.52) | HTTMAPTMAPK8PARP1LMNA | |
| SCHEMBL28323667 | 0.83 | LMNA (0.49) | HTTMAPTNPSR1MAPK8PARP1 | |
| SCHEMBL17009620 | 0.81 | BCAT2 (0.50) | MAPTPARP1LMNAMEN1KMT2A | |
| SCHEMBL2784660 | 0.80 | MAPK8 (0.43) | HTTMAPTNPSR1MAPK8LMNA | |
| SCHEMBL2190365 | 0.80 | ACHE (0.59) | HTTMAPTNPSR1MAPK8ACHE | |
| SCHEMBL25149207 | 0.78 | GAA (0.52) | KMT2AL3MBTL1ALDH1A1BCAT2NPC1 | |
| SCHEMBL7762502 | 0.78 | BCAT2 (0.56) | MAPTNPSR1PARP1LMNAMEN1 | |
| SCHEMBL31541662 | 0.78 | ACHE (0.39) | MAPTMAPK8LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |