SCHEMBL6510160

SCHEMBL6510160

NC1(Cl)C=CC(C(=O)c2ccccc2)C=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
ALOX15 P16050 1/20 0.38
HBB P68871 1/20 0.38
TSHR P16473 2/20 0.38
POLB P06746 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP3A4 P08684 1/20 0.38
PARP1 P09874 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EPHX1 P07099 1/20 0.37
CES1 P23141 4/20 0.35
CES2 O00748 3/20 0.35
ALDH1A1 P00352 2/20 0.35
DAO P14920 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156512 0.85 MAPT (0.40) MAPTHTTALOX15HBBTSHR
SCHEMBL528381 0.85 MAPT (0.40) MAPTHTTALOX15HBBTSHR
SCHEMBL4035521 0.84 ALDH1A1 (0.39) MAPTHTTALOX15HBBTSHR
SCHEMBL7430909 0.82 CES1 (0.38) MAPTHTTALOX15HBBTSHR
SCHEMBL363122 0.81 MAPT (0.40) MAPTHTTALOX15HBBTSHR
Hydrochloric Acid SCHEMBL8844129 0.81 HTT (0.39) MAPTHTTALOX15HBBTSHR
SCHEMBL136598 0.79 MAPT (0.41) MAPTHTTALOX15HBBTSHR
SCHEMBL10586210 0.78 CES2 (0.38) MAPTHTTALOX15HBBTSHR
Acetophenone SCHEMBL6800661 0.78 MAPT (0.42) MAPTHTTALOX15HBBTSHR
SCHEMBL8899432 0.78 GSK3B (0.39) MAPTHTTALOX15HBBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100364968-C Diphenyl ketone photo initiator containing sulfur and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2008-01-30 CN claimed
CN-1850784-A Diphenyl ketone photo initiator containing phenoxy, and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-10-25 CN claimed
CN-1850798-A Diphenyl ketone photo initiator containing sulfur and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-10-25 CN claimed
CN-1727364-A Photoinitiator of benzophenone containing maleimide base group, and preparation method UNIV SHANGHAI JIAOTONG (CN) 2006-02-01 CN claimed
CN-114805133-A Aryl chloroformate preparation method 苏州星日化学有限公司 2022-07-29 CN disclosed
CN-109294457-A Superpower shellproof implosion guard glue film of one kind and preparation method thereof 陈纪霖 2019-02-01 CN disclosed
CN-108276924-A High-transmittance UV-yellowing-resistant hardened film and preparation method thereof 东莞市纳利光学材料有限公司 2018-07-13 CN disclosed
CN-100364968-C Diphenyl ketone photo initiator containing sulfur and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2008-01-30 CN disclosed
CN-1850798-A Diphenyl ketone photo initiator containing sulfur and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-10-25 CN disclosed
CN-1850784-A Diphenyl ketone photo initiator containing phenoxy, and its preparing method UNIV SHANGHAI JIAOTONG (CN) 2006-10-25 CN disclosed
CN-1727364-A Photoinitiator of benzophenone containing maleimide base group, and preparation method UNIV SHANGHAI JIAOTONG (CN) 2006-02-01 CN disclosed
WO-2005037839-A1 NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF ENTOMED (FR) 2005-04-28 WO disclosed
EP-0632017-A1 N-phenyl-2-cyano-3-hydroxy propenamides, their tautomeres and salts, their use as medicaments and compositions containing them ROUSSEL UCLAF (FR) 1995-01-04 EP disclosed