Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528277 | 0.91 | MAPT (0.62) | NPSR1MAPTHTTALDH1A1TP53 | |
| SCHEMBL528351 | 0.90 | MAPT (0.48) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL528383 | 0.87 | NPSR1 (0.65) | NPSR1MAPTHTTALDH1A1TP53 | |
| SCHEMBL528675 | 0.86 | MAPT (0.51) | NPSR1MAPTHTTALDH1A1TP53 | |
| SCHEMBL529288 | 0.84 | MAPT (0.58) | MAPTHTTALDH1A1TP53KDM4E | |
| SCHEMBL529361 | 0.83 | ALDH1A1 (0.50) | MAPTHTTALDH1A1TP53KDM4E | |
| SCHEMBL529586 | 0.81 | MAPT (0.59) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL529419 | 0.79 | MAPT (0.61) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL528500 | 0.78 | MAPT (0.77) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL529212 | 0.77 | NPSR1 (0.48) | NPSR1MAPTHTTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |