Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279608 | 0.86 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5285487 | 0.85 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5126454 | 0.83 | KMT2A (0.69) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5279202 | 0.82 | KMT2A (0.73) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5280353 | 0.81 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5279902 | 0.81 | KMT2A (0.49) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5282184 | 0.80 | L3MBTL1 (0.50) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5282264 | 0.79 | L3MBTL1 (0.58) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5277000 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1NPSR1MAPT | |
| SCHEMBL5287627 | 0.78 | LMNA (0.47) | ALDH1A1KMT2AMEN1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866289-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006097220-A1 | PYRIMIDINE CARBOXYLIC ACID DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-09-21 | — | — | WO | disclosed |