Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529245 | 0.91 | MEN1 (0.52) | MAPTSMN1; SMN2MAPK1TP53RAB9A | |
| SCHEMBL528468 | 0.91 | L3MBTL1 (0.57) | L3MBTL1MAPTSMN1; SMN2MAPK1TP53 | |
| SCHEMBL528401 | 0.90 | MAPT (0.47) | L3MBTL1MAPTSMN1; SMN2MAPK1NPC1 | |
| SCHEMBL528340 | 0.89 | FFAR1 (0.51) | MAPTSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL528660 | 0.89 | L3MBTL1 (0.48) | L3MBTL1MAPTSMN1; SMN2MAPK1TP53 | |
| SCHEMBL529284 | 0.89 | ALDH1A1 (0.56) | L3MBTL1MAPTSMN1; SMN2THRBALDH1A1 | |
| SCHEMBL528937 | 0.89 | MAPT (0.47) | L3MBTL1MAPTSMN1; SMN2MAPK1TP53 | |
| SCHEMBL528274 | 0.87 | L3MBTL1 (0.47) | L3MBTL1MAPTSMN1; SMN2MAPK1TP53 | |
| SCHEMBL528349 | 0.87 | RXFP1 (0.49) | MAPTSMN1; SMN2MAPK1TP53RAB9A | |
| SCHEMBL529397 | 0.86 | MAPT (0.57) | MAPTSMN1; SMN2TP53RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |