Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528572 | 0.91 | RXFP1 (0.48) | MAPTKMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL528272 | 0.90 | MAPT (0.45) | L3MBTL1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL528053 | 0.89 | MAPT (0.55) | MAPTSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL529438 | 0.88 | MAPT (0.54) | MAPTSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL528468 | 0.88 | L3MBTL1 (0.57) | L3MBTL1THRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL528514 | 0.87 | L3MBTL1 (0.49) | L3MBTL1THRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL529284 | 0.85 | ALDH1A1 (0.56) | L3MBTL1THRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL528660 | 0.85 | L3MBTL1 (0.48) | L3MBTL1THRBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL529288 | 0.84 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1TP53HPGD | |
| SCHEMBL529461 | 0.83 | MAPT (0.50) | THRBMAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |