Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528658 | 0.91 | ALDH1A1 (0.53) | SMOKMT2ACNR1CNR2MEN1 | |
| SCHEMBL528340 | 0.91 | FFAR1 (0.51) | KMT2AF2RMEN1MAPTALDH1A1 | |
| SCHEMBL527865 | 0.89 | SMO (0.47) | SMOKMT2ACNR1CNR2GPR27 | |
| SCHEMBL529639 | 0.88 | MAPT (0.55) | SMOKMT2ACNR1CNR2GPR27 | |
| SCHEMBL529397 | 0.88 | MAPT (0.57) | KMT2AF2RMEN1MAPTALDH1A1 | |
| SCHEMBL528626 | 0.87 | ALDH1A1 (0.46) | KMT2ACNR1GPR27MEN1MAPT | |
| SCHEMBL528514 | 0.86 | L3MBTL1 (0.49) | KMT2AMAPTALDH1A1KDM4ETP53 | |
| SCHEMBL528087 | 0.85 | KMT2A (0.55) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL529245 | 0.85 | MEN1 (0.52) | KMT2AMEN1MAPTALDH1A1TP53 | |
| SCHEMBL528262 | 0.85 | MAPT (0.42) | KMT2AMEN1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |