Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528276 | 0.96 | ROCK2 (0.51) | ROCK2MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL528391 | 0.92 | MAPT (0.62) | ROCK2MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL528858 | 0.89 | ROCK2 (0.51) | ROCK2MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL529461 | 0.88 | MAPT (0.50) | ROCK2MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL527918 | 0.88 | HPGD (0.65) | ROCK2MAPTHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL528399 | 0.86 | MAPT (0.56) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL528511 | 0.86 | KMT2A (0.52) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL529259 | 0.83 | MAPT (0.55) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL529579 | 0.83 | MAPT (0.61) | MAPTHTTALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL528111 | 0.83 | MAPT (0.48) | MAPTHTTALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |