Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5275809 | 0.79 | AKR1C3 (0.39) | AKR1C3MTNR1AMTNR1BCHRM4SLC6A4 | |
| SCHEMBL6037910 | 0.72 | CTSS (0.51) | ALDH1A1TSHR | |
| SCHEMBL5287747 | 0.72 | SLC6A4 (0.36) | AKR1C3MTNR1AMTNR1BCHRM4SLC6A4 | |
| SCHEMBL5287833 | 0.71 | LMNA (0.43) | ALDH1A1 | |
| SCHEMBL5410184 | 0.70 | BCHE (0.52) | CHRM4ALDH1A1TSHR | |
| SCHEMBL5282166 | 0.70 | ACHE (0.53) | CHRM4ALDH1A1 | |
| SCHEMBL5282667 | 0.69 | BCHE (0.55) | CHRM4 | |
| SCHEMBL5278902 | 0.69 | BCHE (0.47) | ALDH1A1 | |
| SCHEMBL5281557 | 0.68 | LMNA (0.50) | GRM5ALDH1A1 | |
| SCHEMBL5284999 | 0.67 | CTSS (0.49) | CHRM4ALDH1A1TSHRCHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | claimed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | claimed |