⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122099 | 0.78 | FDPS (0.30) | — | |
| SCHEMBL181414 | 0.72 | PRMT3 (0.33) | — | |
| SCHEMBL1081915 | 0.69 | — | — | |
| SCHEMBL4786657 | 0.69 | — | — | |
| SCHEMBL269617 | 0.67 | — | — | |
| SCHEMBL11471941 | 0.67 | — | — | |
| SCHEMBL25179 | 0.65 | — | — | |
| SCHEMBL28074882 | 0.65 | TDP1 (0.39) | — | |
| SCHEMBL18553317 | 0.65 | LMNA (0.31) | — | |
| SCHEMBL1685481 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | claimed |
| EP-2597955-B1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE INC (JP) | 2016-01-20 | — | — | EP | claimed |
| US-9120749-B2 | Quinoline derivatives and MELK inhibitors containing the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2015-09-01 | — | — | US | claimed |
| US-20130217671-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2013-08-22 | — | — | US | claimed |
| EP-2597955-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | OncoTherapy Science, Inc. (JP) | 2013-06-05 | — | — | EP | claimed |
| WO-2012016082-A1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-02-02 | — | — | WO | claimed |
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-12-16 | — | — | US | claimed |
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | claimed |
| WO-2009065406-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2009-05-28 | — | — | WO | claimed |
| EP-1963331-A1 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | Exelixis, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007070796-A1 | AZEPINOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS, INC. (US) | 2007-06-21 | — | — | WO | claimed |
| EP-1131318-B1 | PROCESS FOR MAKING 5-SUBSTITUTED PYRAZOLES USING DITHIETANES | SEARLE LLC (US) | 2004-03-24 | — | — | EP | claimed |
| EP-2954373-B1 | CHEMICAL COATING FOR A LASER-MARKABLE MATERIAL | FUJIFILM HUNT CHEMICALS US INC (US) | 2019-04-24 | — | — | EP | disclosed |
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | disclosed |
| EP-2597955-B1 | QUINOLINE DERIVATIVES AND MELK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE INC (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2954373-A1 | CHEMICAL COATING FOR A LASER-MARKABLE MATERIAL | Fujifilm Hunt Chemicals US, Inc. (US) | 2015-12-16 | — | — | EP | disclosed |
| EP-0685530-B1 | Process for producing dioxazine compounds, colored materials therewith and dioxazine compounds having a plate-like crystal form | NIPPON KAYAKU KK (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5859242-A | ORGANIC PIGMENTS FOR INKS AND PAINTS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-01-12 | — | — | US | disclosed |
| US-5734050-A | CYCLIZING SUBSTITUTED BIS/CARBAZOLYLAMINO/-1,4-BENZOQUINONE IN PRESENCE OF DIOXAZINE DERIVATIVE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1998-03-31 | — | — | US | disclosed |
| EP-0685530-A1 | Process for producing dioxazine compounds, colored materials therewith and dioxazine compounds having a plate-like crystal form | Nippon Kayaku Kabushiki Kaisha (JP) | 1995-12-06 | — | — | EP | disclosed |