SCHEMBL5287412

SCHEMBL5287412

CCCC(Oc1ccccc1)Oc1ccc(SC)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 5/20 0.40
PPARG P37231 4/20 0.39
PPARA Q07869 4/20 0.39
ALOX5 P09917 2/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
HTR2A P28223 1/20 0.38
KCNH2 Q12809 1/20 0.38
CYP1A2 P05177 2/20 0.37
MEN1 O00255 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LTA4H P09960 3/20 0.36
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6463009 0.86 SLC6A4 (0.43) SLC6A4PPARGPPARASMN1; SMN2LTA4H
SCHEMBL5287783 0.81 CA4 (0.52) PPARGPPARATAS1R3TAS1R1LTA4H
SCHEMBL10596081 0.78 SLC6A4 (0.41) SLC6A4PPARGPPARASMN1; SMN2LTA4H
SCHEMBL5288156 0.77 ALDH1A1 (0.42) SLC6A4HTR2AKCNH2CYP1A2MEN1
SCHEMBL11139896 0.77 SLC6A4 (0.40) SLC6A4PPARGPPARASMN1; SMN2LTA4H
SCHEMBL2993982 0.77 TTR (0.40) SLC6A4PPARGPPARALTA4H
SCHEMBL1579516 0.75 SLC6A4 (0.39) SLC6A4PPARGPPARALTA4H
SCHEMBL17139811 0.75 SLC6A4 (0.39) SLC6A4PPARGPPARASMN1; SMN2LTA4H
SCHEMBL4453544 0.74 LTA4H (0.47) SLC6A4PPARGPPARAALOX5HTR2A
SCHEMBL5282999 0.74 PPARG (0.55) PPARGPPARAKMT2AGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed