Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528937 | 0.92 | MAPT (0.47) | MAPTHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL529518 | 0.90 | MAPT (0.46) | MAPTHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL528632 | 0.90 | ALDH1A1 (0.51) | MAPTHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL528938 | 0.90 | ALDH1A1 (0.59) | MAPTHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL528487 | 0.89 | MAPT (0.46) | MAPTHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL528468 | 0.89 | L3MBTL1 (0.57) | MAPTHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL528272 | 0.88 | MAPT (0.45) | MAPTHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL529428 | 0.88 | MAPT (0.57) | MAPTHTTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL528800 | 0.86 | MAPT (0.62) | MAPTHTTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL528007 | 0.86 | MAPT (0.62) | MAPTHTTALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | claimed |
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |